SQLSTATE[HY000] [2003] Can't connect to MySQL server on '179.188.16.249' (111)

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SQLSTATE[HY000] [2003] Can't connect to MySQL server on '179.188.16.249' (111)
Fatal error: Call to a member function prepare() on a non-object in /home/storage/e/3f/2e/lw135912402951029958/public_html/inc/classe_executa.php on line 31